Lenalidomide, taken in combination with the antibody Rituximab, provides an effective alternative to chemotherapy, according to findings by Jia Ruan, M.D., Ph.D., John Leonard, M.D., and colleagues. Read more
High levels of vitamin C kill colorectal cancers with KRAS and BRAF mutations in cell cultures and mice, according to a new study from Lewis Cantley, Ph.D. Read more
Coverage of a presentation by Ari Melnick, M.D., at the recent Lymphoma & Myeloma 2015 meeting which featured many Weill Cornell organizers and investigators. Read more
Samie Jaffrey and colleagues have discovered mechanisms that control the function of a fat and obesity gene while also answering a long-standing question about how cells respond to stress. Read more
Christopher Barbieri and colleagues shed light on why prostate tumors with a mutation in a gene called SPOP have a high rearrangement frequency Read more
Findings from the lab of Samie Jaffrey, Ph.D., about cap-independent translation in the mRNA of diseased cells IDs a novel pathway that could become a therapeutic target. Read more
A team led by Neal Lue has discovered vulnerabilities in the ALT pathway that investigators might be able to harness for new targeted cancer therapies. Read more
The Cantley lab has gained insight into how alterations in a key metabolic pathway drive non-small cell lung cancers and lead to poor prognosis in its patients. Read more
Many normal-sized men and women have hidden inflamed fat just like obese individuals, which can potentially alter the risk of cancer or its progression, according to new studies by Andrew Dannenberg, M.D., and colleagues. Read more