News

2021 Nov 23

Led by Dr. Jaffrey: National Human Genome Research Institute Funds $12.2 Million Center at Weill Cornell Medicine to Study RNA Modifications

The National Human Genome Research Institute has funded a multi-institutional Center of Excellence in Genome Sciences (CEGS) , based at Weill Cornell Medicine, to develop new tools to study the major product of the human... Read more

2021 Nov 05

Dr. Leandro Cerchietti's Study: Arginine, an Inexpensive Oral Drug, Could Enhance Radiation Therapy for Cancer

Treatment with arginine, one of the amino-acid building blocks of proteins, enhanced the effectiveness of radiation therapy in cancer patients with brain metastases, in a proof-of-concept, randomized clinical trial from... Read more

2021 Oct 14

Dr. Leandro Cerchietti's Study Uncovers a Key Vulnerability of Aggressive Lymphomas

Lymphomas can turbo-charge their ability to proliferate by crowding growth-supporting enzymes into highly concentrated compartments within tumor cells, according to a study led by researchers at Weill Cornell Medicine. The... Read more

2021 Sep 30

Dr. Dan Landau's Study: Powerful Technique Details Brain Tumors’ Formidable Resiliency

A team led by researchers at Weill Cornell Medicine, the New York Genome Center , Harvard Medical School , Massachusetts General Hospital and the Broad Institute of MIT and Harvard has profiled in unprecedented detail... Read more

Illustration of B cells, antibodies and red blood cells. Credit: Shutterstock

2021 Sep 23

Antibody-Producing B Cells May be "Predestined" for their Fates

Illustration of B cells, antibodies and red blood cells. Credit: Shutterstock The master regulator behind the development of antibody-producing cells has been identified in a study by investigators at Weill Cornell Medicine... Read more

Multiplex immunofluorescence image of immune cell-infiltrated human colorectal cancer. Tumor cells are labeled with PKCi (magenta), immune cells are labeled with CD8 (red) and nuclei in white. Image courtesy of Dr. Jorge Moscat.

2021 Sep 23

Enhancing Immune System Discovery of Tumors Might Combat Colorectal Cancer

Multiplex immunofluorescence image of immune cell-infiltrated human colorectal cancer. Tumor cells are labeled with PKCi (magenta), immune cells are labeled with CD8 (red) and nuclei in white. Image courtesy of Dr. Jorge... Read more

Immunofluorescent images of lungs treated with radiation (left) or no radiation (right). Club cells secrete more anti-immunosuppressive factors when treated with radiation, as seen by the increase in the secretory marker CC10 (yellow).

2021 Sep 20

Scientists Find a New Way to Reverse Immune Suppression in Tumors

Primary Image Description & Credit: Immunofluorescent images of lungs treated with radiation (left) or no radiation (right). Club cells secrete more anti-immunosuppressive factors when treated with radiation, as seen by... Read more

2021 Sep 13

Dr. Ashley Laughney's Study: Uveal Melanoma Discovery Points to New Treatment Possibilities

A team co-led by scientists at Weill Cornell Medicine has revealed in detail how the most common primary eye cancer in adults, uveal melanoma (UM), can progress from a slow-growing, “indolent” state to a lethal metastasizing... Read more

Personalized Care: Dr. Gail Roboz (above right), examines patient Cheryl Bonder this spring as part of her ongoing treatment

2021 Sep 07

It’s an Absolute Miracle: Battling a Deadly Blood Cancer, a New Jersey Woman Gets a Second Chance — Thanks to Precision Medicine

Cheryl Bonder had been living with a vaguely defined blood malignancy for years when her prognosis rapidly took a turn for the worse: her condition was progressing toward acute myelogenous leukemia (AML), an aggressive... Read more

Image courtesy of Samuel Taylor and Dr. Marcus Goncalves

2021 Aug 18

Goncalves Lab's Research Uncovers How Fructose in the Diet Contributes to Obesity

Left: Low and high magnification images of small intestine from healthy mice treated with water or high-fructose corn syrup for 4 weeks. Right: Schematic illustrating how fructose promotes cell survival and increased villi... Read more

Artistic rendering of a tumor growing within a colon, resulting in local alterations of resident microbiota. Artist/Image Source: Sarah Field Sonnenberg

2021 Aug 17

Key Immune Cells Maintain Healthy Gut Bacteria to Protect Against Colorectal Cancer

An immune cell subset called innate lymphoid cells (ILC3s) protects against colorectal cancer, in part by helping to maintain a healthy dialogue between the immune system and gut microbes, according to a new study led by... Read more

2021 Aug 02

New Treatment Option for Advanced Urothelial Cancer Patients Shows Promise in a Phase 2 Clinical Trial

A new treatment for advanced urothelial cancer was effective with tolerable side effects in an international, multi-center phase 2 clinical trial led by investigators at Weill Cornell Medicine and NewYork-Presbyterian. The... Read more

Immunofluorescence of a lymph node shows lymphatic endothelial cells contain the enzyme (labeled in green) that generates 3HKA. Image courtesy of Dr. Laura Santambrogio.

2021 Jul 30

Scientists Discover a Powerful Natural Immune-Regulating Molecule

A powerful immune-suppressing molecule produced by the body may hold the key to better treatments for autoimmune and inflammatory diseases, as well as for some cancers, according to a study by researchers at Weill Cornell... Read more

2021 Jul 28

Cancer Vaccine Improves Outcomes in Lynch Syndrome Model

A new strategy for developing vaccines against cancer showed promise in a proof-of-concept study led by scientists at Weill Cornell Medicine, NewYork-Presbyterian and Heidelberg University Hospital. The preclinical results... Read more

2021 Jul 16

Dr. Pinkal Desai's Phase 2 Trial Shows Cell Therapy May Prevent Infections in Leukemia Patients

Treatment with a ready-made preparation of human immune cells helps prevent infections in people whose immune systems are temporarily weakened by leukemia treatment, according to a phase 2 clinical trial led by researchers... Read more

2021 Jul 01

Research Suggests How Tumors Evolve to Become Aggressive Form of Prostate Cancer

Single-cell RNA sequencing of prostate cells from mice with alterations in Pten, RB1 and MYCN identified 10 major cell subtypes and enabled researchers to study tumor heterogeneity with unprecedented resolution. Credit: Dr... Read more

2021 Jun 24

MCC Member & C2i Genomics Co-Founder Dan Landau's Achievement - C2i Genomics Named Finalist for Nature’s Spinoff Prize

Early cancer detection can make all the difference for a patient. Yet many cancers aren’t diagnosed until it’s too late. Drs. Dan Landau and Asaf Zviran are working to develop ultra-sensitive blood tests – called “liquid... Read more

2021 Jun 21

Identifying Social Determinants of Health in Brooklyn

A study from researchers at NewYork-Presbyterian and Weill Cornell Medicine identified economic and social conditions impacting individual and group differences in health status, known as social determinants of health, in... Read more

Radiologist examining a chest X-ray of a patient. Credit: Shutterstock

2021 Jun 15

Combination Therapy Boosts Lung Cancer Patients’ Response, Cuts Treatment Time in Phase 2 Trial

Combining immunotherapy with targeted radiation resulted in a greater response rate than immunotherapy alone in a phase 2 clinical trial in patients with early-stage, non-small-cell lung cancer led by Weill Cornell Medicine... Read more

2021 Jun 09

Breast Cancer Risk in African Americans Tied to Genetic Variations

Two gene variants found in African American women may explain why they are more likely to be diagnosed with triple negative breast cancer (TNBC) than white women of European ancestry, according to Weill Cornell Medicine and... Read more